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A new high resolution radioimager for the quantitative analysis of radiolabelled molecules in tissue section

P. Laniece 1 Y. Charon 1 Alexander Cardona L. Pinot 1 S. Maitrejean R. Mastrippolito 1 B. Sandkamp L. Valentin 1
1 IPNO - Institut de Physique Nucléaire d'Orsay
Abstract : We present a high-speed, high-resolution imager of beta particles. It is devoted to be used in autoradiography experiments such as receptor binding or in situ hybridization experiments, either instead of, or in complement with autoradiographic film and emulsions. It allows the user to locate and perform quantitative analyses of (H-3, C-14, S-35, P-33, P-32, I-125) labelled molecules with a 15 mu m spatial resolution on a 0.9 x 1.3 cm(2) sensitive area. Combining recent techniques (specific scintillator thin sheets and intensified charge-coupled device (CCD)) this imager offers a wide dynamic range and real-time acquisition
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http://hal.in2p3.fr/in2p3-00023030
Contributor : Suzanne Robert <>
Submitted on : Wednesday, April 12, 2000 - 10:13:53 AM
Last modification on : Wednesday, October 14, 2020 - 4:06:04 AM

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  • HAL Id : in2p3-00023030, version 1

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P. Laniece, Y. Charon, Alexander Cardona, L. Pinot, S. Maitrejean, et al.. A new high resolution radioimager for the quantitative analysis of radiolabelled molecules in tissue section. Journal of Neuroscience Methods, Elsevier, 1998, 86, pp.1-5. ⟨in2p3-00023030⟩

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