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The GEANT4-DNA Project

S. Incerti 1 G. Baldacchino 2 M. Bernal R. Capra 3 C. Champion 3 Z. Francis 4 P. Gueye A. Mantero 1 B. Mascialino P. Moretto 1 P. Nieminen 5 C. Villagrasa 4 C. Zacharatou
1 CENBG - Centre d'Etudes Nucléaires de Bordeaux Gradignan
2 IRAMIS - Institut Rayonnement Matière de Saclay
3 LPMC - Laboratoire de physique moléculaire et des collisions
4 IRSN - Institut de Radioprotection et de Sûreté Nucléaire
5 ESTEC - European Space Research and Technology Centre
Abstract : The Geant4-DNA project proposes to develop an open-source simulation software based and fully included in the general-purpose Geant4 Monte-Carlo simulation toolkit. The main objective of this software is to simulate biological damages induced by ionizing radiations at the cellular and sub-cellular scale. This project was originally initiated by the European Space Agency for the prediction of the deleterious effects of radiations that may affect astronauts during future long duration space exploration missions. In this paper, the Geant4-DNA collaboration presents an overview of the whole on-going project, including its most recent developments that are available in the Geant4 toolkit since December 2009 (release 9.3), as well as an illustration example simulating the direct irradiation of a biological chromatin fiber. Expected extensions involving several research domains, such as particle physics, chemistry and cellular and molecular biology, within a fully interdisciplinary activity of the Geant4 collaboration are also discussed.
keyword : Monte-Carlo Geant4 microdosimetry nanodosimetry radiobiology
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http://hal.in2p3.fr/in2p3-00497683
Contributor : Virginie Mas <>
Submitted on : Monday, July 5, 2010 - 4:19:49 PM
Last modification on : Tuesday, May 19, 2020 - 9:14:12 AM

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IN2P3 | IRSN | CENBG | CNRS | CEA | DSM-IRAMIS | UNIV-LORRAINE | CEA-DRF

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S. Incerti, G. Baldacchino, M. Bernal, R. Capra, C. Champion, et al.. The GEANT4-DNA Project. International Journal of Modeling, Simulation, and Scientific Computing, World Scientific Publishing, 2010, 1, pp.157-178. ⟨10.1142/S1793962310000122⟩. ⟨in2p3-00497683⟩

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