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Design of a Compton camera for 3D prompt-γ imaging during ion beam therapy

Abstract : We investigate, by means of Geant4 simulations, a real-time method to control the position of the Bragg peak during ion therapy, based on a Compton camera in combination with a beam tagging device (hodoscope) in order to detect the prompt gamma emitted during nuclear fragmentation. The proposed set-up consists of a stack of 2 mm thick silicon strip detectors and a LYSO absorber detector. The γ emission points are reconstructed analytically by intersecting the ion trajectories given by the beam hodoscope and the Compton cones given by the camera. The camera response to a polychromatic point source in air is analyzed with regard to both spatial resolution and detection efficiency. Various geometrical configurations of the camera have been tested. In the proposed configuration, for a typical polychromatic photon point source, the spatial resolution of the camera is about 8.3 mm FWHM and the detection efficiency 2.5×10−4 (reconstructable photons/emitted photons in 4π). Finally, the clinical applicability of our system is considered and possible starting points for further developments of a prototype are discussed.
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http://hal.in2p3.fr/in2p3-00559943
Contributor : Jeanine Pellet <>
Submitted on : Wednesday, January 26, 2011 - 5:49:06 PM
Last modification on : Wednesday, July 8, 2020 - 12:42:33 PM

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F. Roellinghoff, M.-H. Richard, M. Chevallier, J. Constanzo, D. Dauvergne, et al.. Design of a Compton camera for 3D prompt-γ imaging during ion beam therapy. Imaging 2010, International conference on imaging techniques in subatomic physics, astrophysics, medicine, biology and industry, Jun 2010, Stockholm, Sweden. pp.s20-s23, ⟨10.1016/j.nima.2011.01.069⟩. ⟨in2p3-00559943⟩

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