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Conference papers
Modeling Radiation Chemistry and Biology in the Geant4 Toolkit
M. Karamitros
1
A. Mantero
S. Incerti
1
G. Baldacchino
2
P. Barberet
1
M. Bernal
R. Capra
C. Champion
3
Z. El Bitar
4
Z. Francis
W. Friedland
P. Guèye
A. Ivanchenko
1
V. Ivanchenko
1
H. Kurashige
B. Mascialino
P. Moretto
1
P. Nieminen
5
G. Santin
5
H. Seznec
1
H. N. Tran
C. Villagrasa
6
C. Zacharatou
1
IPCV - Interface Physique et Chimie pour le Vivant
CENBG - Centre d'Etudes Nucléaires de Bordeaux Gradignan
M. Karamitros 1
Author
A. Mantero
Author
S. Incerti 1
Author IdHAL : sebastien-incerti ORCID : https://orcid.org/0000-0002-0619-2053
G. Baldacchino 2
Author
P. Moretto 1
Author
P. Nieminen 5
Author
G. Santin 5
Author
H. Seznec 1
Author IdHAL : herve-seznec ORCID : https://orcid.org/0000-0001-6180-8925
1
IPCV - Interface Physique et Chimie pour le Vivant (France)
- CENBG - Centre d'Etudes Nucléaires de Bordeaux Gradignan (Chemin du Solarium - BP 120 - 33175 Gradignan Cedex - France)
- Université Sciences et Technologies - Bordeaux 1 (351 cours de la Libération - 33405 Talence cedex - France)
- IN2P3 - Institut National de Physique Nucléaire et de Physique des Particules du CNRS (France)
- CNRS - Centre National de la Recherche Scientifique : UMR5797 (France)
2
IRAMIS - Institut Rayonnement Matière de Saclay (91191 Gif-sur-Yvette, France - France)
- CEA - Commissariat à l'énergie atomique et aux énergies alternatives : DRF/IRAMIS (Centre de Saclay Centre de Grenoble Centre de Cadarache etc - France)
- Université Paris-Saclay (Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin - France)
3
LPMC - Laboratoire de physique moléculaire et des collisions (Institut de Physique 1 boulevard Arago Technopôle 2000 57078 Metz cedex 3 - France)
4
IPHC - Institut Pluridisciplinaire Hubert Curien (23 rue Loess - BP 28 67037 Strasbourg Cedex - France)
- UNISTRA - Université de Strasbourg (4 rue Blaise Pascal - CS 90032 - 67081 Strasbourg cedex - France)
- IN2P3 - Institut National de Physique Nucléaire et de Physique des Particules du CNRS (France)
- CNRS - Centre National de la Recherche Scientifique : UMR7178 (France)
5
ESTEC - European Space Research and Technology Centre (Keplerlaan 1, 2201 Noordwijk - Netherlands)
- ESA - European Space Agency (France)
Abstract : Simulation of biological effects of ionizing radiation at the DNA scale requires not only the modeling of direct damages induced on DNA by the incident radiation and by secondary particles but also the modeling of indirect effects of radiolytic products resulting from water radiolysis. They can provoke single and double strand breaks by reacting with DNA. The Geant4 Monte Carlo toolkit is currently being extended for the simulation of biological damages of ionizing radiation at the DNA scale in the framework of the "Geant4-DNA" project. Physics models for the modeling of direct effects are already available in Geant4. In the present paper, an approach for the modeling of radiation chemistry in pure liquid water within Geant4 is presented. In particular, this modeling includes Brownian motion and chemical reactions between molecules following water radiolysis. First results on time-dependent radiochemical yields1 from 1 picosecond up to 1 microsecond after irradiation are compared to published data and discussed.
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Conference papers
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http://hal.in2p3.fr/in2p3-00658865
Contributor : Nathalie Martin Connect in order to contact the contributor
Submitted on : Wednesday, January 11, 2012 - 2:58:17 PM
Last modification on : Friday, March 5, 2021 - 3:10:28 PM
Contributor : Nathalie Martin Connect in order to contact the contributor
Submitted on : Wednesday, January 11, 2012 - 2:58:17 PM
Last modification on : Friday, March 5, 2021 - 3:10:28 PM
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- HAL Id : in2p3-00658865, version 1
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Citation
M. Karamitros, A. Mantero, S. Incerti, G. Baldacchino, P. Barberet, et al.. Modeling Radiation Chemistry and Biology in the Geant4 Toolkit. 3rd Monte Carlo Conference MC2010, Oct 2010, Tokyo, Japan. pp.503-508. ⟨in2p3-00658865⟩
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