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Validation of GATE 6.1 for targeted radiotherapy of metastic melanoma using 131I-labeled benzamide

Abstract : The GATE 6.1 Monte Carlo simulation platform based on the GEANT4 toolkit is in constant improvement for dosimetric calculations. Here, we explore its use for calculating internal absorbed dose distribution in mice for the treatment of malignant melanoma after injection of a new specific radiopharmaceutical labeled with iodine 131. We estimate the dosimetric accuracy of GATE 6.1, by calculating first S values and by comparing them and absorbed doses to organswith EGSnrc for a digital mouse phantom and a CT scan based mouse phantom.
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http://hal.in2p3.fr/in2p3-00703187
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Submitted on : Friday, June 1, 2012 - 10:22:55 AM
Last modification on : Thursday, June 11, 2020 - 3:19:14 AM
Long-term archiving on: : Sunday, September 2, 2012 - 2:22:25 AM

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Y. Perrot, L. Maigne, Vincent Breton, D. Donnarieix. Validation of GATE 6.1 for targeted radiotherapy of metastic melanoma using 131I-labeled benzamide. Third European Workshop on Monte Carlo Treatment Planning, May 2012, Seville, Spain. 5 p. ⟨in2p3-00703187⟩

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