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Poster communications

Physical characterization of a wireless radiotracer detection system based on pixalated Silicon for in vivo brain studies in freely moving rats

Abstract : An exciting challenge for neuro-physiological investigations remains the combination of brain imaging and behavioral studies, which associates molecular processes of neuronal communications to their related actions. PIXSIC presents novel strategy using a submillimeter pixellated probe for β+ radiotracer detection based on a reverse-biased, high-resistivity silicon diode; This fully autonomous detection system permits local, time resolved measurements of radiotracers in a volume of a few mm3 with the probe dipped into aqueous solutions of [18F] and [11C]. Preliminary implantation tests on a anaesthetized rats proved functionality of the PIXSIC probe in brain tissues. High spatial resolution allows for the visualization of radiotracer concentration in different brain regions with a temporal resolution of less than 2 seconds
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Poster communications
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http://hal.in2p3.fr/in2p3-00767714
Contributor : Danielle Cristofol <>
Submitted on : Thursday, December 20, 2012 - 12:31:02 PM
Last modification on : Monday, December 14, 2020 - 6:10:46 PM

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  • HAL Id : in2p3-00767714, version 1

Citation

Julia Maerk, Didier Benoit, Laure Balasse, Mathieu Benoit, Jean-Claude Clémens, et al.. Physical characterization of a wireless radiotracer detection system based on pixalated Silicon for in vivo brain studies in freely moving rats. IX ième Journée Scientifique BCP, Dec 2012, Marseille, France. ⟨in2p3-00767714⟩

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