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Monte Carlo simulation of energy-deposit clustering for ions of the same LET in liquid water
Francis Z., Incerti S., Ivanchenko V., Champion C., Karamitros M. et al
Physics in Medicine and Biology 57 (2012) 209-224 - http://hal.in2p3.fr/in2p3-00664486
Physique/Physique/Physique Médicale
Monte Carlo simulation of energy-deposit clustering for ions of the same LET in liquid water
Z. Francis, S. Incerti1, V. Ivanchenko1, C. Champion2, M. Karamitros1, M. A Bernal, Z. El Bitar3
1 :  CENBG - Centre d'Etudes Nucléaires de Bordeaux Gradignan
http://www.cenbg.in2p3.fr/
CNRS : UMR5797 – IN2P3 – Université Sciences et Technologies - Bordeaux I
Chemin du Solarium - BP 120 - 33175 Gradignan Cedex
France
2 :  LPMC (EA 3468) - Laboratoire de physique moléculaire et des collisions
http://www.univ-metz.fr/recherche/equipederecherche/physique/lpmc/
Université Paul Verlaine - Metz
Institut de Physique 1 boulevard Arago Technopôle 2000 57078 Metz cedex 3
France
3 :  IPHC - Institut Pluridisciplinaire Hubert Curien
CNRS : UMR7178 – Université de Strasbourg
France
IPCV
This work presents a Monte Carlo study of energy depositions due to protons, alpha particles and carbon ions of the same linear-energy-transfer (LET) in liquid water. The corresponding track structures were generated using the Geant4-DNA toolkit, and the energy deposition spatial distributions were analyzed using an adapted version of the DBSCAN clustering algorithm. Combining the Geant4 simulations and the clustering algorithm it was possible to compare the quality of the different radiation types. The ratios of clustered and single energy depositions are shown versus particle LET and frequencymean lineal energies. The estimated effect of these types of radiation on biological tissues is then discussed by comparing the results obtained for different particles with the same LET.

Articles dans des revues avec comité de lecture
07/01/2012
Physics in Medicine and Biology (Phys Med Biol)
Publisher Institute of Physics: Hybrid Open Access
ISSN 0031-9155 (eISSN : 1361-6560)
57
209-224