19 articles – 50 references  [version française]
HAL: hal-00688280, version 1

Short view  Export this paper
Toward non-linear endomicroscopy for exploration of the pulmonary airways : preliminary spectroscopic study of human lung tissue using monomode fiber
Peyrot D., Abi Haidar D., Lefort C., Sandeau N., Mansuryan T. et al
in Prococeedings SPIE 7893 - Endoscopic Microscopy VI, Nonlinear Endomicroscopy, San franscisco - Californie : United States (2011) - http://hal.archives-ouvertes.fr/hal-00688280
Toward non-linear endomicroscopy for exploration of the pulmonary airways : preliminary spectroscopic study of human lung tissue using monomode fiber
Donald Peyrot1, Darine Abi Haidar2, Claire Lefort ()3, Nicolas Sandeau, Tigran Mansuryan ()3, Frédéric Louradour ()3, Sergei Kruglik, Geneviève Bourg-Heckly
1:  LOA - Laboratoire d'optique appliquée
http://wwwy.ensta.fr/loa/
CNRS : UMR7639 – ENSTA ParisTech – Polytechnique - X
Chemin de la Hunière 91761 PALAISEAU CEDEX
France
2:  IMNC - Imagerie et Modélisation en Neurobiologie et Cancérologie
CNRS : UMR8165 – IN2P3 – Université Paris XI - Paris Sud – Université Paris VII - Paris Diderot
BATIMENT 104 15 Rue Georges Clémenceau 91406 ORSAY CEDEX
France
3:  XLIM - XLIM
http://www.xlim.fr
CNRS : UMR6172 – Université de Limoges
123 Avenue Albert THOMAS 87060 LIMOGES CEDEX
France
PHOTONIQUE
We are developing a non-linear fibered endomicroscope for imaging the extracellular matrix collagen and elastin fibrillar networks during bronchoscopy. As a proof of concept, laser pulses at the output of a standard 2 meter long single-mode fibre have been obtained with pulse duration of about 50 fs and pulse energy up to 50 uJ, using a specially designed grism line for the dispersion compensation. With these pulses, we performed a spectroscopic characterization of the non-linear endogenous signal, consisting of two-photon fluorescence and second harmonic generation, and originated from human pulmonary tissue of various thickness, both in forward and backward geometry of signal collection, with excitation at 830 nm.
English
2011

Proc. SPIE 7893
Prococeedings SPIE 7893
international
Conference proceedings
2011
7893
n°789309

Endoscopic Microscopy VI, Nonlinear Endomicroscopy
2011-01-23
2011-01-23
San franscisco - Californie
United States