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Publications de l'IMNC |  |
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Publications de l'IMNC | |
| HAL : hal-00688280, version 1 |
| DOI : 10.1117/12.875440 |
| Fiche détaillée |  Récupérer au format |
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| Endoscopic Microscopy VI, Nonlinear Endomicroscopy, San franscisco - Californie : États-Unis (2011) |
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| Toward non-linear endomicroscopy for exploration of the pulmonary airways : preliminary spectroscopic study of human lung tissue using monomode fiber |
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| Donald Peyrot1Darine Abi Haidar2Claire Lefort3Nicolas SandeauTigran Mansuryan3Frédéric Louradour3Sergei KruglikGeneviève Bourg-Heckly |
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| (2011) |
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| We are developing a non-linear fibered endomicroscope for imaging the extracellular matrix collagen and elastin fibrillar networks during bronchoscopy. As a proof of concept, laser pulses at the output of a standard 2 meter long single-mode fibre have been obtained with pulse duration of about 50 fs and pulse energy up to 50 uJ, using a specially designed grism line for the dispersion compensation. With these pulses, we performed a spectroscopic characterization of the non-linear endogenous signal, consisting of two-photon fluorescence and second harmonic generation, and originated from human pulmonary tissue of various thickness, both in forward and backward geometry of signal collection, with excitation at 830 nm. |
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| 1 : | LOA - Laboratoire d'optique appliquée |
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| 2 : | IMNC - Imagerie et Modélisation en Neurobiologie et Cancérologie |
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| 3 : | XLIM - XLIM |
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| PHOTONIQUE |
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| hal-00688280, version 1 | |
| http://hal.archives-ouvertes.fr/hal-00688280 | |
| oai:hal.archives-ouvertes.fr:hal-00688280 | |
| Contributeur : Véronique Maury | |
| Soumis le : Mardi 17 Avril 2012, 11:37:23 | |
| Dernière modification le : Mardi 17 Avril 2012, 11:47:02 | |
