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Cardiovascular Rehabilitation in Patients With Diabetes.
Mourot L., Boussuges A., Maunier S., Chopra S., Rivière F. et al
J Cardiopulm Rehabil Prev (2009) epub ahead of print - http://hal.archives-ouvertes.fr/hal-00451987
Sciences du Vivant/Médecine humaine et pathologie
Cardiovascular Rehabilitation in Patients With Diabetes.
Laurent Mourot1, 2, Alain Boussuges3, S. Maunier, S. Chopra, F. Rivière4, X. Debussche5, P. Blanc
1 :  CIC - Biotherapie - Besancon
INSERM : CBT506 – IFR133 – CHU Besançon
Hôtel Saint-Martin 2, Place Saint-Jacques 25030 Besançon Cedex
France
2 :  PCVP - Physiopathologie Cardiovasculaire et Prévention
http://ifr133-ibct.univ-fcomte.fr/EA.htm
Université de Franche-Comté : EA3920 – IFR133 – CHU Besançon
Faculté de Médecine et de Pharmacie de Besançon rue Ambroise Paré (Hauts du Chazal) 25030 Besançon
France
3 :  IMNSSA - Institut de Médecine Navale du Service de Santé des Armées
Service de Santé des Armées
BP 610 83800 Toulon Naval.
France
4 :  CPPM - Centre de Physique des Particules de Marseille
http://marwww.in2p3.fr/
CNRS : UMR7346 – IN2P3 – Université de la Méditerranée - Aix-Marseille II
163, avenue de Luminy - Case 902 - 13288 Marseille cedex 09
France
5 :  IBCP - Institut de biologie et chimie des protéines [Lyon]
http://www.ibcp.fr
CNRS : UMR5086 – Université Claude Bernard - Lyon I
7 Passage du Vercors 69367 LYON CEDEX 07
France
PURPOSE: The cardiovascular disease risk profile and exercise capacity of coronary heart disease patients with type 2 diabetes mellitus (DM) were measured and compared with those of nondiabetic (NDM) patients before and after a 6-week multidisciplinary cardiac rehabilitation program. METHODS: Subjects included 413 patients with DM (56.9 +/- 7.9 years) and 614 patients with NDM (56.8 +/- 10.3 years). RESULTS: At program entry, DM patients had a higher prevalence of risk factors (hypertension, hypercholesterolemia, hypertriglyceridemia, obesity, excess abdominal fat, and depression), had a lower peak oxygen uptake (14.3 +/- 4.4 vs 16.6 +/- 5.4 mL . kg . min; P < .001), and covered a shorter distance in the 6-minute walk test (404 +/- 117 m vs 445 +/- 116 m; P < .001) than NDM patients. At the end of the exercise program, all patients achieved significant improvements in physical capacity, which were similar in DM and NDM patients (+27.6 +/- 28.2% vs +30.5 +/- 27.7% for peak oxygen uptake and +21.0 +/- 31.5% vs +21.3 +/- 53.2% for the 6-minute distance test). CONCLUSION: DM patients with coronary heart disease had a higher prevalence of cardiovascular disease risk factors as well as lower physical capacity than NDM patients at the beginning of rehabilitation. All patients demonstrated improvement in exercise capacity after rehabilitation. More importantly, the extent of the improvement was similar in DM and NDM patients. This study, which involved a large population, emphasizes the capacity of DM patients to fully benefit from a multidisciplinary risk factor management program, including exercise training and educational programs.
Anglais

J Cardiopulm Rehabil Prev
internationale
Articles dans des revues avec comité de lecture
25/12/2009
25/12/2009
epub ahead of print