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Stereotactic and Functional Neurosurgery 88, 3 (2010) 129-37
A target-specific electrode and lead design for internal globus pallidus deep brain stimulation.
Xavier Vasques1, Laura Cif1, Gerard Mennessier2, Philippe Coubes1

In nearly all deep brain stimulation (DBS) applications, the same quadripolar electrode design is used for different anatomical targets even if shape and volume differences exist between nuclei. Taking into account the electrode location within the internal globus pallidus (GPi) and the size of the GPi, 2 electrodes were designed in order to improve the therapeutic benefit, to minimize side effects from DBS and to obtain a more homogeneous electric field distribution. The electrodes were evaluated numerically by using a stereotactic model measuring the correlation between the electric field and the GPi. The model was applied to 26 dystonodyskinetic patients who underwent surgery for a bilateral lead implantation into the posteroventral part of the GPi. The designed electrodes produced a more homogeneous distribution of the electric field than the quadripolar electrode.
1 :  IGF - Institut de génomique fonctionnelle
2 :  LPTA - Laboratoire de Physique Théorique et Astroparticules
Sciences du Vivant/Neurosciences/Neurobiologie
Deep brain stimulation – Dystonodyskinetic syndromes – Globus pallidus internus – Stereotactic model – Electrode design