[Exposure to fine air particles and occurrence of allergic diseases: results of ISAAC-France phase 2].

I. Annesi-Maesano; D. Caillaud; F. Lavaud; D. Moreau; Y. Le Moullec; A. Taytard; G. Pauli; D. Charpin

HAL : hal-00595449, version 1

PubMed : 19211233

DOI : 10.1016/j.arcped.2008.12.004

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(Exposure to fine air particles and occurrence of allergic diseases: results of ISAAC-France phase 2).
Annesi-Maesano I., Caillaud D., Lavaud F., Moreau D., Le Moullec Y. et al
Archives de Pédiatrie 16, 3 (2009) 299-305 - http://hal.upmc.fr/hal-00595449

Domaine :

Sciences du Vivant/Santé publique et épidémiologie

Titre :

[Exposure to fine air particles and occurrence of allergic diseases: results of ISAAC-France phase 2].

Auteur(s) :

I. Annesi-Maesano (

)¹, D. Caillaud, F. Lavaud², D. Moreau³, Y. Le Moullec⁴, A. Taytard, G. Pauli, D. Charpin

Laboratoire :

1 :	ESIM - Epidémiologie des maladies infectieuses et modélisation

http://www.u707.jussieu.fr

INSERM : U707 – Université Pierre et Marie Curie [UPMC] - Paris VI

Faculte de Médecine Saint-Antoine 27, Rue Chaligny 75571 Paris Cedex 12

France

2 :	IPNO - Institut de Physique Nucléaire d'Orsay

http://ipnweb.in2p3.fr

CNRS : UMR8608 – IN2P3 – Université Paris XI - Paris Sud

IPN - 15, rue Georges Clemenceau - 91406 ORSAY CEDEX

France

3 :	Service de réanimation médicale

Assistance publique - Hôpitaux de Paris (AP-HP) – Hôpital Saint-Louis – Université Paris VII - Paris Diderot

1 rue Claude Vellefaux 75011 Paris

France

4 :	LSGC - Laboratoire des Sciences du Génie Chimique

http://www.inpl-nancy.fr/ENSIC/LSGC/LSGC.html

CNRS : UPR6811

1, rue Grandville BP 20451 54001 NANCY cedex

France

Résumé :

To evaluate whether fine air particles could be involved in the occurrence of atopy and allergic diseases, we performed a cross-sectional epidemiological survey involving primary schoolchildren living in six French towns with contrasted air pollution levels. Air pollution was measured during a week in the school yards and by standard air monitoring networks. Children get an examination in school looking for atopic dermatitis and bronchial hyperresponsiveness assessed by a standardized run test. Besides, parents or guardians provided past medical history and environmental data, especially on passive smoking. Overall, 5,338 children, aged 10.4 (+/-0.7) years, coming from 108 different schools and 401 different classes were included in the survey. Taking into account potential confounders, high exposure to proximity PM(2.5) was linked to a higher point prevalence of atopic dermatitis and hyperresponsiveness, to a higher cumulative prevalence of allergic asthma and a higher sensitization rate to common indoor allergens. Thus, these data suggest that chronic exposure to urban fine particles could be a risk factor for atopy, hyperresponsiveness and asthma.

Langue du texte
intégral :

Français

Pôle UPMC :

Pôle 4 vie et sante

Projet(s), collaboration(s) :

Annesi-Maesano I, Caillaud D, Lavaud F, Moreau D, Le Moullec Y, Taytard A, Pauli G, Charpin D.

Journal :

Archives de Pédiatrie (Arch Pediatr)
Publisher	Elsevier
ISSN	0929-693X

Audience :

internationale

Type de publication :

Articles dans des revues avec comité de lecture

Date de publication :

03/2009

Date de publication
électronique :

10/02/2009

Volume :

Numéro :

Page, identifiant, ... :

299-305

Descripteur(s) MeSH :

Air Pollution – Asthma – Bronchial Hyperreactivity – Child – Cross-Sectional Studies – Dermatitis – Atopic – Environmental Exposure – Female – France – Health Surveys – Humans – Male – Particle Size – Population Surveillance


hal-00595449, version 1
http://hal.upmc.fr/hal-00595449
oai:hal.upmc.fr:hal-00595449
Contributeur : Isabella Annesi-Maesano <>
Soumis le : Mardi 24 Mai 2011, 17:45:58
Dernière modification le : Mardi 24 Mai 2011, 17:45:58