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Influence of Geant4 parameters on dose distribution and computation time for carbon ion therapy simulation.
Zahra N., Frisson T., Grevillot L., Lautesse P., Sarrut D.
Physica Medica 26, 4 (2010) 202-8 - http://hal.archives-ouvertes.fr/hal-00633360
Sciences du Vivant/Ingénierie biomédicale
Influence of Geant4 parameters on dose distribution and computation time for carbon ion therapy simulation.
N. Zahra1, 2, 3, T. Frisson1, 2, 3, L. Grevillot2, 3, P. Lautesse1, D. Sarrut2, 3
1 :  IPNL - Institut de Physique Nucléaire de Lyon
http://www.ipnl.in2p3.fr/
CNRS : UMR5822 – IN2P3 – Université Claude Bernard - Lyon I (UCBL)
France
2 :  CREATIS - Centre de recherche en applications et traitement de l'image pour la santé
http://www.creatis.insa-lyon.fr/
Institut National des Sciences Appliquées [INSA] – CNRS : UMR5220 – Université Claude Bernard - Lyon I (UCBL) – INSERM : U1044 – Hospices Civils de Lyon
7 avenue Jean Capelle, Bat Blaise Pascal, 69621 Villeurbanne Cedex
France
3 :  Centre Léon Bérard
CRLCC Léon Bérard
28, rue Laennec 69373 LYON Cedex 08
France
matiere nucleaire
The aim of this work was to study the influence of Geant4 parameters on dose distribution and computational time for simulations of carbon ion therapy. The study was done using Geant4 version 9.0. The dose distribution in water for incident monoenergetic carbon ion beams of 300 MeV/u were compared for different values of secondary particle production threshold and different step limits. Variations of depth dose of about 2 mm were observed in some cases, which induced a 30% variation of dose deposit in the Bragg peak region. Other tests were done using Geant4 version 9.2 to verify the results from this study. The two versions provided converging results and led to the same conclusions.
Anglais

Physica Medica
Publisher Elsevier
ISSN 1120-1797 
internationale
Articles dans des revues avec comité de lecture
10/2010
27/01/2010
26
4
202-8

Carbon – Humans – Models – Biological – Neoplasms – Radiation Dosage – Radiotherapy Dosage – Software – Time Factors – Tomography – X-Ray Computed – Uncertainty

CCIN2P3