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Imaging 2010, International conference on imaging techniques in subatomic physics, astrophysics, medicine, biology and industry, Stockholm : Suède (2010)
Design of a Compton camera for 3D prompt-γ imaging during ion beam therapy
F. Roellinghoff1, 2, M.-H. Richard1, 2, M. Chevallier1, J. Constanzo1, D. Dauvergne1, N. Freud2, P. Henriquet1, F. Le Foulher1, J.M. Létang2, G. Montarou3, C. Ray1, E. Testa1, M. Testa1, A.H. Walenta
GEANT4 Collaboration(s)

We investigate, by means of Geant4 simulations, a real-time method to control the position of the Bragg peak during ion therapy, based on a Compton camera in combination with a beam tagging device (hodoscope) in order to detect the prompt gamma emitted during nuclear fragmentation. The proposed set-up consists of a stack of 2 mm thick silicon strip detectors and a LYSO absorber detector. The γ emission points are reconstructed analytically by intersecting the ion trajectories given by the beam hodoscope and the Compton cones given by the camera. The camera response to a polychromatic point source in air is analyzed with regard to both spatial resolution and detection efficiency. Various geometrical configurations of the camera have been tested. In the proposed configuration, for a typical polychromatic photon point source, the spatial resolution of the camera is about 8.3 mm FWHM and the detection efficiency 2.5×10−4 (reconstructable photons/emitted photons in 4π). Finally, the clinical applicability of our system is considered and possible starting points for further developments of a prototype are discussed.
1 :  IPNL - Institut de Physique Nucléaire de Lyon
2 :  CNDRI - Controle Non Destructif par Rayonnements Ionisants
3 :  LPC - Laboratoire de Physique Corpusculaire [Clermont-Ferrand]
Sciences du Vivant/Ingénierie biomédicale/Imagerie

Physique/Physique/Physique Médicale

Compton camera – hadrontherapy – ion beam therapy – prompt gamma – Geant4