| HAL : in2p3-00559943, version 1 |
| DOI : 10.1016/j.nima.2011.01.069 |
| Fiche détaillée | Récupérer au format |
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| Imaging 2010, International conference on imaging techniques in subatomic physics, astrophysics, medicine, biology and industry, Stockholm : Suède (2010) |
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| Design of a Compton camera for 3D prompt-γ imaging during ion beam therapy |
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| F. Roellinghoff1, 2M.-H. Richard1, 2M. Chevallier1J. Constanzo1D. Dauvergne1N. Freud2P. Henriquet1F. Le Foulher1J.M. Létang2G. Montarou3C. Ray1E. Testa1M. Testa1A.H. Walenta |
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| GEANT4 Collaboration(s) |
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| (2011) |
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| We investigate, by means of Geant4 simulations, a real-time method to control the position of the Bragg peak during ion therapy, based on a Compton camera in combination with a beam tagging device (hodoscope) in order to detect the prompt gamma emitted during nuclear fragmentation. The proposed set-up consists of a stack of 2 mm thick silicon strip detectors and a LYSO absorber detector. The γ emission points are reconstructed analytically by intersecting the ion trajectories given by the beam hodoscope and the Compton cones given by the camera. The camera response to a polychromatic point source in air is analyzed with regard to both spatial resolution and detection efficiency. Various geometrical configurations of the camera have been tested. In the proposed configuration, for a typical polychromatic photon point source, the spatial resolution of the camera is about 8.3 mm FWHM and the detection efficiency 2.5×10−4 (reconstructable photons/emitted photons in 4π). Finally, the clinical applicability of our system is considered and possible starting points for further developments of a prototype are discussed. |
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| 1 : | IPNL - Institut de Physique Nucléaire de Lyon |
| 2 : | CNDRI - Controle Non Destructif par Rayonnements Ionisants |
| 3 : | LPC-CLERMONT - Laboratoire de Physique Corpusculaire de Clermont-Ferrand |
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| CAS-PHABIO |
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| Thème(s) | : | Sciences du Vivant/Ingénierie biomédicale/Imagerie Physique/Physique/Physique Médicale Physique/Physique/Biophysique |
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| Compton camera – hadrontherapy – ion beam therapy – prompt gamma – Geant4 |
| in2p3-00559943, version 1 | |
| http://hal.in2p3.fr/in2p3-00559943 | |
| oai:hal.in2p3.fr:in2p3-00559943 | |
| Contributeur : Jeanine Pellet | |
| Soumis le : Mercredi 26 Janvier 2011, 17:49:06 | |
| Dernière modification le : Lundi 4 Février 2013, 12:52:19 | |