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The LPT is based at the University of Toulouse. It has been founded in 1991 and its administrative structure was established in 2003. Before 2003, researchers where rassembled in the Group of Theoretical Physics. This group was hosted by the Laboratoire de Physique Quantique (now LCPQ).

The LPT is member of IRSAMC (The Institute of Research on Complex Atomic and Molecular Systems).

=> There publications before 2003: HAL-LPQ_GPT

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[hal-02297365] Google matrix analysis of bi-functional SIGNOR network of protein-protein interactions

Directed protein networks with only a few thousand of nodes are rather complex and do not allow to extract easily the effective influence of one protein to another taking into account all indirect pathways via the global network. Furthermore, the different types of activation and inhibition actions between proteins provide a considerable challenge in the frame work of network analysis. At the same time these protein interactions are of crucial importance and at the heart of cellular functioning. We develop the Google matrix analysis of the protein-protein network from the open public database SIGNOR. The developed approach takes into account the bi-functional activation or inhibition nature of interactions between each pair of proteins describing it in the frame work of Ising-spin matrix transitions. We also apply a recently developed linear response theory for the Google matrix which highlights a pathway of proteins whose PageRank probabilities are most sensitive with respect to two proteins selected for the analysis. This group of proteins is analyzed by the reduced Google matrix algorithm which allows to determine the effective interactions between them due to direct and indirect pathways in the global network. We show that the dominating activation or inhibition function of each protein can be characterized by its magnetization. The results of this Google matrix analysis are presented for three examples of selected pairs of proteins. The developed methods work rapidly and efficiently even for networks with several million of nodes and can be applied to various biological networks.

[hal-02045594] What is the central bank of Wikipedia?


[hal-02309051] Gravitational phase transitions and instabilities of self-gravitating fermions in general relativity


[hal-02266627] Regularities in the spectrum of chaotic p-modes in rapidly rotating stars


[hal-03012420] Kinetic theory of one-dimensional homogeneous long-range interacting systems with an arbitrary potential of interaction