In this paper we present an analysis strategy and a dedicated tool to determine the exclusion confidence level for any scenario involving multiple heavy extra quarks with generic decay channels, as predicted in several extensions of the Standard Model. We have created, validated and used a software package, called XQCAT (eXtra Quark Combined Analysis Tool), which is based on publicly available experimental data from direct searches for top partners and from Supersymmetry inspired searches. The code will soon be publicly available and will be upgraded to include data from new searches. By means of this code, we recast the limits from CMS on new heavy extra quarks considering a complete set of decay channels. The resulting exclusion confidence levels are presented for some simple scenarios with multiple states and general coupling assumptions. Highlighting the importance of combining multiple topology searches to obtain accurate re-interpretations of the existing searches, we discuss the reach of the SUSY analyses so as to set bounds on new quark resonances. In particular, we report on the re-interpretation of the existing limits on benchmark scenarios with one and multiple pair-produced top partners having non-exclusive couplings to the third Standard Model generation of quarks.