In this paper we consider realistic model of inflation embedded in the framework of loop quantum cosmology. Phase of inflation is preceded here by the phase of a quantum bounce. We show how parameters of inflation depend on the initial conditions established in the contracting, pre-bounce phase. Our investigations indicate that phase of the bounce easily sets proper initial conditions for the inflation. Subsequently we study observational effects that might arise due to the quantum gravitational modifications. We perform preliminary observational constraints for the Barbero-Immirzi parameter $\gamma$, critical density $\rho_{\text{c}}$ and parameter $\lambda$. In the next step we study effects on power spectrum of perturbations. We calculate spectrum of perturbations from the bounce and from the joined bounce+inflation phase. Based on these studies we indicate possible way to relate quantum cosmological models with the astronomical observations. Using the Sachs-Wolfe approximation we calculate spectrum of the super-horizontal CMB anisotropies. We show that quantum cosmological effects can, in the natural way, explain suppression of the low CMB multipoles. We show that fine-tuning is not required here and model is consistent with observations. We also analyse other possible probes of the quantum cosmologies and discuss perspectives of their implementation.