A rapid microwave-assisted procedure for easy access to Nx polydentate ligands for potential application in α-RIT
Résumé
Heterocycles bearing a hydrazine moiety react with bisaldehydes or bisketones to afford new Nx polydentate ligands suitable for α-radioimmunotherapy. We developed a fast and efficient method using microwave-assisted technology to obtain chelators with variable size and number of coordination centres which were fully characterized. The complexation efficiency with astatine will be assessed.
Domaines
Radiochimie
Origine : Fichiers produits par l'(les) auteur(s)
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