Physical characterization of a wireless radiotracer detection system based on pixalated Silicon for in vivo brain studies in freely moving rats - IN2P3 - Institut national de physique nucléaire et de physique des particules Access content directly
Conference Poster Year : 2012

Physical characterization of a wireless radiotracer detection system based on pixalated Silicon for in vivo brain studies in freely moving rats

Mathieu Benoit

Abstract

An exciting challenge for neuro-physiological investigations remains the combination of brain imaging and behavioral studies, which associates molecular processes of neuronal communications to their related actions. PIXSIC presents novel strategy using a submillimeter pixellated probe for β+ radiotracer detection based on a reverse-biased, high-resistivity silicon diode; This fully autonomous detection system permits local, time resolved measurements of radiotracers in a volume of a few mm3 with the probe dipped into aqueous solutions of [18F] and [11C]. Preliminary implantation tests on a anaesthetized rats proved functionality of the PIXSIC probe in brain tissues. High spatial resolution allows for the visualization of radiotracer concentration in different brain regions with a temporal resolution of less than 2 seconds

Domains

Imaging
No file

Dates and versions

in2p3-00767714 , version 1 (20-12-2012)

Identifiers

  • HAL Id : in2p3-00767714 , version 1

Cite

Julia Maerk, Didier Benoit, Laure Balasse, Mathieu Benoit, Jean-Claude Clémens, et al.. Physical characterization of a wireless radiotracer detection system based on pixalated Silicon for in vivo brain studies in freely moving rats. IX ième Journée Scientifique BCP, Dec 2012, Marseille, France. ⟨in2p3-00767714⟩
27 View
0 Download

Share

Gmail Facebook X LinkedIn More